WebOct 6, 2024 · Bryan B Hsu 1 2 3 , Isaac N Plant 4 5 , Lorena Lyon 4 5 , Frances M Anastassacos 5 6 , Jeffrey C Way 4 5 ... To facilitate phage administration while minimizing disruption to host processes, we develop an aqueous-based encapsulation formulation with a microbiota-based release mechanism and show that it facilitates oral delivery of phage … Web(540) 231-4246 Current Research We are broadly interested in using an inter-disciplinary approach (microbiology, synthetic biology, and biomaterials) towards understanding and remodeling the gut microbiota. We are especially focused on discovering new phages and genetically engineering them for anti-bacterial and anti-virulence applications.
Dynamic Modulation of the Gut Microbiota and Metabolome by ...
WebNational Center for Biotechnology Information WebHsu BB, Plant IN, Lyon L, Anastassacos FM, Way JC, Silver PA. In situ reprogramming of gut bacteria by oral delivery. Nature Communications. 11: 5030. PMID 33024097 DOI: 10.1038/s41467-020-18614-2 : 0.92: 2024: Hsu BB, Way JC, Silver PA. Stable Neutralization of a Virulence Factor in Bacteria Using Temperate Phage in the … hillsborough ca planning adrb
Dr. Candace Bryan, MD, Neurology Fairfax, VA WebMD
Webtemperate phage, i.e., one that integrates itself into the bacterial genome, to neu-tralize the expression of a virulence factor by modifying bacterial function at the ge-netic level. We show that Shiga toxin production can be significantly reduced in vitro and in the mammalian gut. Alternative to traditional applications of phage WebJul 8, 2024 · Bryan White 30, Andy Whiteley 50, Katrine L. Whiteson 63, ... Evolutionary and genomic studies have suggested that dynamic phage–host interactions are reflected in phage genomes, ... WebOct 16, 2024 · Phage DC-56 was classified into cluster DC and phage DS-92 into cluster DS, according to the similarity with other Gordonia phages and members of the corresponding mycobacteriophage clusters [44, 45]. hillsborough calendar 2022