Phospho-upf1
WebAnti-phospho-Upf1 (Ser1127), Cat. No. 07-1016, is a highly specific rabbit polyclonal antibody that targets Regulator of nonsense transcripts 1 (RENT1) phosphorylated at Ser1127 and has been tested in Immunoprecipitation, peptide … WebPan Phospho-Tyrosine (2) Phospho Y705 (1) MonoMethyl K4 (1) Phospho S9 (1) DiMethyl K9 (1) DiMethyl K4 (2) Unconjugated (11) Phospho Y15 (1) TriMethyl K36 (2) Phospho S15 (1) ... UPF1 UPF1; DNMT1 DNMT1; FURIN FURIN; ACLY ACLY; ALDH1A1 ALDH1A1; PROM1 PROM1; MCAM MCAM; CD62P CD62P; P-SELECTIN P-SELECTIN; CALR CALR; CLTC …
Phospho-upf1
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WebAug 11, 2016 · Increase in phospho-UPF1 on ARE-mediated decay activation Given the observed hyperphosphorylation of UPF1 in response to mRNA decay factor depletion, we … WebMay 29, 2010 · Compared with WT, GT tMEFs showed reduced levels of an anti–phospho-S/T-Q antibody–detected band comigrating with Upf1 in both the lysate and anti-Upf1 immunoprecipitate (Fig. 1E). This result confirms that disruption of Smg1 expression in Smg1 gt/gt embryos reduces the phosphorylation levels of Upf1.
WebFeb 4, 2024 · Western blot analysis demonstrated downregulation of phospho-UPF1, SMG7, and eIF4A3 in Atf4 knockdown cells compared to NS siRNA-transfectants under mild ER … WebDec 1, 2024 · The most conserved NMD factors are up-frameshift proteins ( UPF) UPF1, UPF2 and UPF3B. The human NMD machinery additionally is comprised of suppressors with morphogenetic effects on genitalia (SMG) proteins including SMGs 1, 5, 6, 7, 8, and 9. SMG1 forms a complex with SMG8 and SMG9 which downregulate SMG1’s kinase activity [ 35 ].
WebSep 29, 2011 · SMG-1-mediated Upf1 phosphorylation takes place in the decay inducing complex (DECID), which contains a ribosome, release factors, Upf1, SMG-1, an exon junction complex (EJC) and a PTC-mRNA. However, the significance and the consequence of Upf1 phosphorylation remain to be clarified. WebImmunoprecipitation of phospho-UPF1 (Ser1107) protein from HeLa cell extracts. Lane 1 is 10% input, lane 2 is Normal Rabbit IgG #2729, and lane 3 is Phospho-UPF1 (Ser1107) …
WebPhospho-eIF2alpha (Ser51) Antibody detects endogenous eIF2alpha only when phosphorylated at Ser51. The antibody does not recognize elF2alpha phosphorylated at other sites. Human eIF2alpha residue Ser52 historically …
WebHuman up-frameshift 1 (UPF1) is an ATP-dependent RNA helicase and phosphoprotein implicated in several biological processes but is best known for its key function in nonsense-mediated mRNA decay (NMD). Here we employed a combination of stable isotope labeling of amino acids in cell culture experiments to determine by quantitative proteomics UPF1 … trust wallet crypto customer service numberWebDec 10, 2024 · Fig. 3: Correlation of NMD efficiency with NMD regulator SMG1 and phosphorylation of UPF1. Simultaneous detection of fluorescence NMD reporter and SMG1, or phospho-UPF1 (PUPF1). a, d... philips bluetooth mp3 playerWebDownload scientific diagram Replication stress results in increased phosphorylation of UPF1 but not HBP/SLBP on PIKK substrate motifs. Asynchronous HeLa cells were incubated with or without 2 mM ... philips bluetooth micro music systemWebJul 3, 2024 · UPF1 overexpression protects neurons from R-DPR toxicity Consistent with the notion that R-DPRs cause neurodegeneration in part through inhibiting NMD, recent studies have shown that... philips bluetooth mp3WebAnti-phospho-Upf1 (Ser1127), Cat. No. 07-1016, is a highly specific rabbit polyclonal antibody that targets Regulator of nonsense transcripts 1 (RENT1) phosphorylated at … philips bluetooth light stripWebThe UPF1 gene has been cloned and sequenced and shown to be (1) nonessential for viability, (2) capable of encoding a 109-kDa protein with both zinc finger and nucleotide (GTP) binding site motifs, and (3) partially homologous to the yeast SEN1 gene ( … trustwallet dapps browserWebSep 29, 2011 · SMG-1-mediated Upf1 phosphorylation takes place in the decay inducing complex (DECID), which contains a ribosome, release factors, Upf1, SMG-1, an exon junction complex (EJC) and a PTC-mRNA.... trust wallet ethereum main sweeper bot